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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 6.97
Human Site: T305 Identified Species: 10.95
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 T305 G P Y P A A P T F G S Q P G P
Chimpanzee Pan troglodytes XP_001145058 1094 118246 T305 S P Y P A A P T F G S Q P G P
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 Q276 P P M H S P Q Q P G Y Q P Q Q
Dog Lupus familis XP_850963 1096 118584 P306 G S P Y P G A P T F G S Q P G
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 P308 A P P V A G M P P P S L S Y P
Rat Rattus norvegicus NP_001102926 1095 118506 P305 E S P Y P G A P T F G T Q P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 Q306 T D C V I Q D Q G N A S P R Y
Chicken Gallus gallus XP_421617 1147 124543 N362 G A Y P G T P N Y G S Q P G P
Frog Xenopus laevis NP_001087832 1126 123503 G305 H M P S S Q D G F P P Q Q N G
Zebra Danio Brachydanio rerio XP_700597 1315 142554 Y305 P P G P S Q S Y G G P L P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 G415 P L P G Q S A G Q M I N S G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 G348 G M P P Q G G G V G G Y G Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 I314 P N Q S M T N I P T A M G Q P
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 P154 Q D S D N Q V P L N T D G V I
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 T228 A P K Y V R S T L N A V P T T
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 93.3 26.6 6.6 N.A. 26.6 0 N.A. 6.6 66.6 13.3 26.6 N.A. N.A. 6.6 N.A. 26.6
P-Site Similarity: 100 93.3 33.3 6.6 N.A. 26.6 0 N.A. 13.3 73.3 20 33.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 6.6 0 20
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 0 20 14 20 0 0 0 20 0 0 0 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 0 0 14 0 0 0 0 7 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 20 14 0 0 0 0 0 % F
% Gly: 27 0 7 7 7 27 7 20 14 40 20 0 20 27 20 % G
% His: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 7 0 0 7 0 0 0 7 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 0 0 0 0 0 0 14 0 0 14 0 0 0 % L
% Met: 0 14 7 0 7 0 7 0 0 7 0 7 0 0 0 % M
% Asn: 0 7 0 0 7 0 7 7 0 20 0 7 0 7 0 % N
% Pro: 27 40 40 34 14 7 20 27 20 14 14 0 47 20 40 % P
% Gln: 7 0 7 0 14 27 7 14 7 0 0 34 20 20 7 % Q
% Arg: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % R
% Ser: 7 14 7 14 20 7 14 0 0 0 27 14 14 0 0 % S
% Thr: 7 0 0 0 0 14 0 20 14 7 7 7 0 7 14 % T
% Val: 0 0 0 14 7 0 7 0 7 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 20 0 0 0 7 7 0 7 7 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _